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Result: ADSC transplantation provided durable relief in fibromyalgia patients by enhancing tissue oxygenation, reducing oxidative stress, and downregulating central sensitization markers

This interplay is partially mediated by neuropeptides such as calcitonin gene receptor peptide (CGRP), pituitary adenylate cyclase activating polypeptide (PACAP) and/or cortical spreading depression (CSD) and involves oxidative stress, mitochondrial dysfunction, nucleotide-binding domain-like receptor family pyrin domain containing-3 (NLRP3) inflammasome formation, activated microglia, and reactive astrocytes

Une cure de 6 8 semaines est gnralement conseille pour observer des effets visibles, notamment sur l'clat de la peau